Differential Transcriptional Responses to Interferon-α and Interferon-γ in Primary Human Hepatocytes
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چکیده
منابع مشابه
Epitope Mapping of Neutralizing Monoclonal Antibodies to Human Interferon-γ Using Human-Bovine Interferon-γ Chimeras
Our aim was to identify conformational epitopes, recognized by monoclonal antibodies (mAbs) made against human (h) interferon (IFN)-γ. Based on the mAbs' (n = 12) ability to simultaneously bind hIFN-γ in ELISA, 2 epitope clusters with 5 mAbs in each were defined; 2 mAbs recognized unique epitopes. Utilizing the mAbs' lack of reactivity with bovine (b) IFN-γ, epitopes were identified using 7 h/b...
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ژورنال
عنوان ژورنال: Journal of Interferon & Cytokine Research
سال: 2010
ISSN: 1079-9907,1557-7465
DOI: 10.1089/jir.2009.0082